Roberto Mancini's side travel to in-form Newcastle knowing they must secure all three points if they are to stay top of the table, with the Red Devils hosting Swansea afterwards
Manchester City head into Sunday's clash at Newcastle knowing one slip could leave them behind Manchester United in the Premier League title race once again.
City travel to Tyneside in the knowledge that if they can secure three points it will more than likely mean they will be crowned champions on the final day of the season. However, Alan Pardew's men are flying high in fifth spot and fighting for that all-important Champions League place, and with Papiss Cisse in the team anything seems possible at the moment.
Sir Alex Ferguson will be hoping for a favour from the Toon, and will also have to make sure his own side do a professional job of beating Swansea at Old Trafford. If City slip up and United secure three points it will take United back to the top with one game remaining.
Another fixture with consequences at both ends of the table is Aston Villa against Tottenham. Spurs will be looking to build on their 4-1 demolition of Bolton in the week as they try to secure the final Champions League spot and overhaul Arsenal in third, while Alex McLeish's side sit just three points above the relegation places, and could slip further into trouble if results don't go their way.
QPR will be looking to build on their recent impressive home form with a win over Stoke on Sunday. Mark Hughes' men have beaten Liverpool and Arsenal in recent weeks at Loftus Road and know a victory over Tony Pulis' side could help secure their position in the Premier League for one more season.
Elsewhere, Bolton host West Brom in a game they must win to have any chance of avoiding the drop. Meanwhile Fulham clash with Sunderland and relegated Wolves will be attempting to stop the resurgent Everton and Nikica Jelavic.